Imitating the positive effects of exercise Nature.com

Physical activity is demonstrated to help prevent and treat various illnesses, including Type 2 Diabetes and obesity. But, the molecular mechanisms which are involved in these benefits are not fully known. Writing in Nature, Li et al. report that exercise stimulates the production of the metabolite N-lactoyl-phenylalanine (Lac-Phe) in mice, horses and humans. Additionally, the injection of Lac-Phe into obese mice reduced the appetite and weight gain.

doi: https://doi.org/10.1038/d41573-022-00110-5

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